Bayesian Reciprocal LASSO Composite Quantile Regression for Robust Clinical Risk Modeling
Abstract
Clinical data often contain outliers and irrelevant predictors that can distort inference and reduce the reliability of traditional regression methods. To address this issue, we propose a robust Bayesian variable selection framework by integrating composite quantile regression with a reciprocal LASSO prior. The method accommodates heavy-tailed errors and performs simultaneous coefficient estimation and sparsity enforcement.We evaluate the proposed model through extensive simulation studies under contamination scenarios and compare it with classical and Bayesian LASSO-based quantile regression methods. The model is further applied to systolic blood pressure data from the NHANES 2017–2018 survey to identify key lifestyle and health-related predictors. Results show that the proposed method outperforms competing approaches in terms of predictive accuracy, robustness to outliers, and variable selection stability.
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